Thursday, September 29, 2016

Zika virus infection 2015-16 Epidemic - Update #5



Zika virus infection 2015-16 Epidemic
September 6, 2016 Update
Paul Herscu ND, MPH
Herscu Laboratory

Zika Virus Disease And Targeted Vector Control ‘The Future is Already Here — Just Not Evenly Distributed’

This article addresses only one aspect of prevention of Zika virus caused disease; it is the fifth in a series. For previous writings on the subject and to contextualize this writing, please refer to my blog.

I had previously written on the vector control benefits of attempting ‘functional’ extinction of the Aedes aegypti species that likely carries Yellow fever, Dengue fever, Chikungunya, and Zika virus, illnesses that lead to morbidity or mortality in the many thousands every year. The arguments were many, but the main point was that Zika virus was absolutely going to impact the health of Americans via local transmission and that many would suffer needlessly. I went on to urge that the time was right for the planned ‘functional’ extinction of Aedes aegypti but at this point that approach would no longer be sufficient. As expected, we have since seen the first infant death in the U.S., due to Zika virus and have the first U.S. birth of a child with Zika virus caused microcephaly. More that 2,722 people in the U.S. have been infected, with 35 from local transmission, according to the CDC Case Counts in the U.S. Sadly, more will likely follow.

Monday, April 25, 2016

Zika virus infection 2015-16 Epidemic - Update #4


Zika virus infection 2015-16 Epidemic
April 12, 2016 Update
Paul Herscu ND, MPH
Herscu Laboratory

The Time is NOW for Some Mosquitoes to Go

This article deals with only one aspect of prevention of Zika virus caused disease, and is the fourth of a series. For previous writings on the subject and to contextualize this writing, see: http://www.paulherscuepidemics.blogspot.com/

When my older son was entering middle school, he and I attended several Bioblitz events, which are 24-hour inventories of all species in a certain area. We got into the concept, after he read a book written by E.O. Wilson, Consilience. He later met Dr. Wilson, exchanged correspondence, joined the Explorer's Club and eventually gave lectures on the concept of the bioblitz. He also had the idea of connecting the E.O. Wilson's Encyclopedia of Life (http://eol.org) project with the Bioblitz events that occur in the National Parks of the USA. If you want to read about how the Bioblitz concept began, please see this link: 

The reason I highlight this concept is to say that my family is and has always been very environmentally friendly. We have worked for and continue to work towards a stable, robust biodiversity, not only for trophy, keystone, or umbrella species, but for all species. Diversity is essential for our own species to survive and thrive.

That said, and as an environmentalist, I believe the time has arrived for us, as a species, to drive into functional extinction a few mosquito species or species groups. The reasons are compelling, rational, ethical, and scientific. I would like to place this topic in context.

Monday, March 28, 2016

Zika virus infection 2015-16 Epidemic - Update #3


Zika virus infection 2015-16 Epidemic
March 24, 2016 Update
Paul Herscu ND, MPH
Herscu Laboratory

If you have not yet read my first posting on this topic, please do so now before reading the following.
As mentioned in prior longer posts, my intention was to lay a foundation and build scaffolding so that when you see data or hear the news or learn of novel discoveries, you will have enough history and adequate context to make sense of it and have an informed opinion, making it easier for everyone to both predict what the news will be, and to anticipate government and scientific next steps. And as I finished that post, I mentioned that if I did my job well, the next posts would be short as the scaffolding would be in place and the forecasts made, only needing to be confirmed. If you have not read those posts please do so, as they will help place the discussion in context. You can find them HERE. The specific variables I chose to focus on remain the same:

1. Will Zika virus impact the USA?
2. Does Zika virus cause neurological diseases or is it some other agent?
3. Is Aedes aegypti the only vector we have to worry about?
4. How to address the intersection of economics and infections.
5. The role of Prevention.

Let’s dive in

Tuesday, February 16, 2016

Zika virus infection 2015-16 Epidemic - Update #2

Zika virus infection 2015-16 Epidemic
February 11, 2016 Update
Paul Herscu, ND, MPH
Herscu Laboratory

If you have not yet read my first posting on this topic, please do so now before reading the following.

My intention with this post is to continue to lay a foundation and build scaffolding so that when you see data or hear the news or learn of novel discoveries, you will have enough history and adequate context to make sense of it and have an informed opinion. These writings should also make it easier for everyone to both predict what the news will be, and to anticipate government and scientific next steps. Here we are focusing on Zika virus, but really the discussion of Zika virus lies within a larger framework. As such I am going to describe a few variables below. They relate to the topic of germs in general and Zika virus specifically. In this update, I describe briefly, the placement of people within biology, the relationship of Zika virus and neurological diseases, vector and coinfection issues, economic issues, and ultimately prevention. At the end of this reading, I expect many of your questions will be answered and much of the future news may find a more logical place.

Into the Water

I am writing this part in the Florida Everglades, within the home range of the Aedes aegypti mosquito. One of my sons and I just finished handling alligators and snakes and now I am about to have lunch. And it occurs to me that these are ‘dirty’ creatures, by which I mean they carry any number of little critters, let alone bacteria and viruses on their skin, which might make me sick. Maybe I should wash my hands extra special! While this may seem like those were exotic creatures, a more common American example would be pet turtles under 4 inches and frogs in the USA that can make the very young, old, or immune compromised people sick or even kill them with Salmonella infections. At its height, the problem was so great, the FDA stepped in to ban the transportation of turtles in the USA. 
Or:

Thursday, February 4, 2016

Zika virus infection 2015-16 Epidemic - Update #1


Zika virus infection 2015-16 Epidemic
January 2016 Update
Paul Herscu, ND, MPH
Herscu Laboratory


We have just passed over a milestone that I want to highlight, to place the discussion about Zika virus in a very important context. We have just had a twelfth case of Zika virus infection diagnosed in the USA. This number is significant to me, since it is exactly one more patient than the total number of Ebola virus disease (EVD) patients to have hit USA soil from the Ebolavirus 2014 Outbreak in Western Africa. That number includes those who developed EVD in Africa and were transported here and those who fell ill from human transmission inside the USA.
I believe it is of upmost importance to place any discussion of Zika virus infection within an EVD context for a variety of reasons. When I commented on EVD, both in this Blog  and in the Webinar I presented on Viruses, I made some very strong comments and predictions. These were based on tracking viral infection outbreaks and epidemics around the worlds for several decades.
One point I highlighted was as we look at the history of our species and its effect on other species on this planet one thing becomes clear. As we have explored, conquered, inhabited and thrived in a variety of environments around the planet, when we found a species that was large-toothed, venomous, and scary, we would try to destroy it, driving the species towards extinction. We feel more comfortable when they are not threatening us. Right or wrong this is what we have done. And as we have begun to feel more comfortable in our surroundings, we began to look more closely at what may be the new scary things to our species–germs, bacteria and viruses. And as our technology has gotten better, cheaper, more accurate and specific, we are better able to isolate an ever-increasing diverse microcosm, both outside and inside of our bodies. In short, we have relearned that we are not alone. And again, reflexively, we are frightened. An added fear is the continued realization that an ever-larger number of bacteria become scarier as we encourage their evolution with and toward antibiotic resistance.